Reveal all classes of structural variants using Bionano’s optical genome mapping Stratys™ System. Explore the Stratysphere!

Introducing VIA – a complete and integrated solution for the visualization, interpretation and reporting of genomic variants

Existing data analysis solutions for genomics are laborious, time-consuming and incomplete. You have to manage various systems, navigate complex workflows and spend inordinate amounts of time hunting for annotations and creating data visualizations. Good news: those days are over. VIA software radically simplifies your sample-to-report workflow and empowers you to deliver more clinically relevant answers from across technologies faster. VIA brings various data types into one view and automates variant calling, interpretation and annotation, so you can reduce turnaround times and optimize operations at every step.

How it Works

Variant Intelligence Applications™ software is the only analysis software that combines secondary and tertiary analysis, receiving and interpreting data from optical genome mapping (OGM), next-generation sequencing (NGS) and microarrays to contextualize all classes of genomic variation and drive meaningful insights.


Instant Visualization, Zero Hassle. Automate Data Display for Powerful Insights.

VIA software amplifies the story of your data by automatically generating powerful visualizations for enhanced variant contextualization across multiple variant types happening in the same genomic region.

VIA allows you to drill down to single chromosome, gene, and nucleotide levels for deeper analysis. Leverage multiple views, including genome browser, karyogram, track view, and circos plot.


Put Your Analysis on Autopilot and Get to What Matters Faster.

VIA software introduces intelligent automation for filtering, classifying, annotating and interpreting data across technologies, no more hours manually searching through databases.

VIA accelerates time to results to drive faster, informed interpretations while reducing associated costs.

  • Annotate: Integrate gene/variant annotation from external databases and previously reported variants from historical data.
  • Filter: Automatically classify variants using a rules-based engine, dynamically filter against curated datasets and remove irrelevant variants.
  • Interpret: Capture expert interpretation from analysts automatically and implement case signoffs.


Flexible Reporting that Simplifies Decision Making.

Easily create reports communicating results with simplicity and clarity thanks to VIA’s customizable reporting options. Bring the most relevant information to the surface along with visuals and data that support decision-making that meet guideline-based requirements.

VIA also provides the option for utilizing the new hematological malignancy workflow for a streamlined analysis and reporting solution for OGM data. See the Application Spotlight.


A Single Platform for All Your Variant Data.

VIA eliminates complex data analysis workflows by bringing data types together in one centralized platform, including your historical data from previous cases. You can seamlessly transition between technologies and all classes of genomic variation within VIA software.

  • View and analyze OGM, NGS, and microarray data without switching between systems.
  • Perform analysis of structural variants, copy-number variants, allelic imbalances, single nucleotide variants and indels for enhanced discovery of causative findings that may be missed if analyzed independently
  • Retain and recall historical case interpretations for faster analyses.

Application Spotlight

The latest versions of Bionano Solve, Bionano Access™, and VIA software combine to deliver a comprehensive and automated workflow for analyzing, interpreting, and reporting SVs and CNVs detected by OGM associated with hematological malignancies.

This complete workflow leverages intelligent software automation to reduce the time to result for hematological malignancy sample data from OGM, including curated resources in VIA software that represent guideline-based targets applicable to hematological disease. VIA software automatically pre-classifies variants detected with OGM according to a rules-based engine to classify events based on pathogenicity or variant tiering system.

These oncology workflows are configurable to your site-specific preferences.

Comparison of Bionano Software Capabilities

See how VIA software compares to other Bionano data analysis software.

Feature VIA Access NxClinical 6.2
Data Visualization
Genome Browser Visualization
Circos Plot Visualization
OGM Molecule Maps (links to Access)
Variant Calling
B-Allele Frequency Plot for OGM
Integrated HRD Scar Analysis
T2T Human Genome
Interpretation and Reporting
Automated Variant Classification
Robust Gene/Variant Annotations
Local Variant Database
Integrated Knowledgebase
Connection to MasterMind
ACMG-based CNV Scoring
Dynamic Variant Filtering
Heme Guideline Analysis
Configurable Report Generation
Data Integration
OGM Data Compatibility
NGS & Array Data Integrations
CNV/AOH Analysis
Structural Variant Analysis
Sequence Variant Analysis

Expert Insights

Learn More about VIA Software

Watch a short video explaing how VIA works

Watch Video

Read more about homologous recombination deficiency and how Bionano VlA software provides in-depth analysis of HRD

Read White Paper

Learn more about the value of integrating multiple datasets. Download a list of recent publications where OGM was combined with NGS to investigate disease cases.

Download Summary

Experience VIA in Action

Hear What Some of our Customers Say About Their Experience with Bionano Software Solutions in Their Research

“At the UCSD clinical genetics lab, we are tasked with providing a complete and clinically actionable genomic profile of a tumor. NₓClinical allows us to do this rapidly and comprehensively by allowing us to consider CNV, LOH, and sequence variants together within a single software.”

Dr. Sarah Murray
Director of Genomics Technologies, UC San Diego, CA, USA

“Bionano software is able to use NGS and microarray data for the assessment of HRD using the same bioinformatic pipeline is very helpful and looking forward to doing the same analysis with OGM.”

Christopher Lum, MD
Medical Director, Molecular Diagnostics Laboratory at Diagnostic Laboratory Services, Inc.

Downloads and Resources

See How the Software Works

Talk to a specialist to discuss how you can benefit from VIA in more detail or request a demo to review the software to see how it can detect and analyze genome-wide variation.

Contact Us

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