This video covers CNV calling algorithms. Common approaches, HMM (Hidden Markov Model), CBS (circular binary segmentation), and Rank Segmentation are covered along with a discussion of the pros and cons of each algorithm.

 

Download our white paper, “Analyzing NGS Data For Copy Number Events,” to learn:

• How to use the BAM algorithm to obtain both copy number and allelic events from NGS data (unique and exclusive to Nexus Copy Number)
• Why this Read-Depth method is the most reliable and efficient means to extracting copy number information out of NGS data
• How the algorithm compares to other CNV estimating algorithms such as CoNIFER and XHMM

Download White Paper →

Want to learn more?

View our webinar recording on integrated analysis of sequence variations and copy number in TCGA data with Nexus Copy Number.

View webinar recording →